Also Called a mastocytoma, mast cell tumours (MCT’s) are skin tumours Which have arisen from mast cells, which are a sort of white blood cell formed in the bone marrow. Mast cells are found throughout the body but are concentrated at points of contact between the cat and the outside world, particularly the skin, respiratory tract, gastrointestinal tract, and conjunctiva.
Mast cell tumours can develop in different areas such as the skin (dermal), or internally (like the spleen, liver or gastrointestinal tract), called visceral or disseminated. Cutaneous tumours can in some cases, spread to regional lymph nodes and on to the inner organs (most commonly the spleen or liver), or tumours can develop in the organs with no skin involvement. Highly aggressive tumours can enter bone marrow (which makes all of the blood cells) and turn up in the bloodstream.
Mast cell tumours are the second most common skin tumour in cats, the most Frequent splenic tumour and the third most frequent sort of intestinal tumour. Nearly all mast cell tumours are benign (non-spreading), but around 10 percent are cancerous (which could spread to other areas of the body).
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Mast cells are a part of the immune system and are involved in the Inflammatory process and are responsible for the allergic reactions many people (and creatures) experience. They do it by releasing granules, called degranulation. Granules have a variety of active compounds which perform these functions:
Histamine — Vasodilation (widening of the blood vessels), increase vascular permeability and stimulates the nerve end.
Heparin — Prevents the formation of blood clots.
If the cat (or individual) has undergone an accident or a pathogen, Degranulation is a fantastic thing, but sometimes mast cells respond to normally harmless substances, such as pollen, causing the allergy-related symptoms like hives and itchy skin.
The cause is unknown, but it believed There’s a genetic component due to A high prevalence in Siamese cats.
Single or multiple hairless nodules (lumps) on or underneath the skin. They can happen anywhere on the body including the head, neck, chest, limbs and anogenital area. Tumours vary in size from 1 to 4 cm and can wax and wane in size. They may be well defined or ill-defined. Ill-defined tumours are more aggressive.
From time to time nodules may become inflamed and itchy, as a result of a release of histamine in the tumour.
Up to 25 percent of tumours may possess some degree of ulceration due to self-trauma.
Systemic symptoms may present with cats that have visceral mast cell tumours, which may include:
Your vet will perform a physical examination and obtain a medical history from you. Tests will be required to diagnose mast cell tumour, these may include:
Staging is necessary to determine the extent of the disease; there are three grades.
- Moderately differentiated
- Poorly differentiated.
Your cat will probably be discharged with an Elizabethan collar to prevent self-trauma Of the surgery website.
Antibiotics, painkillers, and antihistamines will be given to alleviate symptoms.
Keep a close eye on the operation site and if you notice any swelling, redness Or oozing, talk to your vet.